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Machine translation
1. (WO1982000465) PROCESS FOR PREPARING VITAMIN D-LACTONES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1982/000465    International Application No.:    PCT/US1981/000961
Publication Date: 18.02.1982 International Filing Date: 16.07.1981
IPC:
C07D 307/33 (2006.01), C07J 17/00 (2006.01), C07J 9/00 (2006.01)
Applicants: WISCONSIN ALUMNI RESEARCH FOUNDATION
Inventors:
Priority Data:
Title (EN) PROCESS FOR PREPARING VITAMIN D-LACTONES
(FR) PROCEDE DE PREPARATION DE VITAMINES D-LACTONES
Abstract: front page image
(EN)Methods for preparing the various isomeric forms of 25-hydroxyvitamin D3-26, 23-lactone utilizing cyanohydrin formation with readily prepared steroid materials followed by actinic radiation of the products and recovery of the desired 25-hydroxyvitamin D3-26, 23-lactone. The invention also provides new intermediate compounds in their various isomeric forms derived during the process for preparing the said vitamin D3 lactones. 25-Hydroxyvitamin D3-26, 23-lactone is recognized as having vitamin D-like activity and is believed to play an important role in the regulation of calcium and phosphate levels in the animal and human organism. The present invention provides a convenient method for preparing the various isomeric forms of this compound.
(FR)Procedes de preparation des differentes formes isomeres de 25-hydroxyvitamine D3-26,23-lactone utilisant la formation de cyanohydrine avec des materiaux steroides deja prepares suivie d'une irradiation actinique des produits et d'une recuperation de 25-hydroxyvitamine D3-26,23-lactone. L'invention concerne egalement de nouveaux composes intermediaires dans leurs diverses formes isomeres derivees pendant le procede pour preparer ces vitamines D3 lactones. La 25-hydroxyvitamine D3-26,23-lactone est reconnue comme ayant une activite semblable a la vitamine D et l'on croit savoir qu'elle joue un role important dans la regulation des niveaux de calcium et de phosphate dans les organismes des animaux et des etres humains. La presente invention fournit un procede approprie de preparation des diverses formes isomeres de ce compose.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)