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Machine translation
1. (WO1982000141) 3-AMINO-PROPOXY-PHENYL DERIVATIVES,PREPARATION THEREOF AND DRUGS CONTAINING THEM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1982/000141    International Application No.:    PCT/CH1981/000074
Publication Date: 21.01.1982 International Filing Date: 07.07.1981
IPC:
A61K 31/135 (2006.01), A61K 31/165 (2006.01), A61K 31/275 (2006.01), A61K 31/40 (2006.01), C07C 217/30 (2006.01), C07C 255/49 (2006.01), C07C 255/53 (2006.01), C07C 43/00 (2006.01), C07D 303/24 (2006.01)
Applicants: SANDOZ AG
Inventors:
Priority Data:
Title (EN) 3-AMINO-PROPOXY-PHENYL DERIVATIVES,PREPARATION THEREOF AND DRUGS CONTAINING THEM
(FR) DERIVES DU 3-AMINO-PROPOXY-PHENYLE, LEUR PREPARATION ET REMEDES LES CONTENANT
Abstract: front page image
(EN)Compounds having the formula I (FORMULA) wherein the symbols have the meanings given in claim 1. Also derivatives, physiologically acceptable and susceptible of hydrolysis are included, derivatives wherein the hydroxy group in position 2 of the lateral chain 3-amino-propoxy is esterified, and the salts thereof. All these compounds have, as a pharmacological activity, an anti-arhythmic action and block the adrenoceptors (Alpha) and (Beta). Consequently they may be used as drugs. They are obtained by amination, optionally followed by esterification.
(FR)Composes de formule I (FORMULE) dans laquelle les symboles portent les significations donnees en revendication (1). Sont inclus egalement les derives physiologiquement acceptables et susceptibles d'hydrolyse; derives dans lesquels le groupe hydroxy en position (2) de la chaine laterale 3-amino-propoxy se trouve esterifie, ainsi que leurs sels; tous ces composes presentent, en tant qu'activite pharmacologique, une action anti-arythmique et bloquent les adrenocepteurs (Alpha) et (Beta). Ils peuvent en consequence etre utilises en tant que remedes. On les obtient par amination, suivie eventuellement d'esterification.
Designated States:
Publication Language: German (DE)
Filing Language: German (DE)