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Machine translation
1. (WO1982000099) POLYMERIC DIFFUSION MATRIX FOR ADMINISTRATION OF DRUGS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1982/000099    International Application No.:    PCT/US1981/000893
Publication Date: 21.01.1982 International Filing Date: 26.06.1981
IPC:
A61K 31/565 (2006.01), A61K 9/00 (2006.01), A61K 9/70 (2006.01)
Applicants: KEY PHARMACEUTICALS, INCORPORATED
Inventors:
Priority Data:
Title (EN) POLYMERIC DIFFUSION MATRIX FOR ADMINISTRATION OF DRUGS
(FR) MATRICE POLYMERE DE DIFFUSION POUR ADMINISTRER DES MEDICAMENTS
Abstract: front page image
(EN)A polymeric diffusion matrix for administering a drug is provided comprising from about 2 to about 60% of a polar plasticizer, e.g., glycerol, from about6 to about 20% of polyvinylalcohol, from about 2 to about 10% of polyvinylpyrrolidone, and a pharmaceutically effective amount of drug, yielding a matrix capable of sustained release of a vasodilator drug dispersed therein, and the balance water, the percentages being by weight. The drugs include terbutaline, ephedrine, clonidine, phenylephrine, estradiol esters, phenylpropanolamine, and chlorpheniramine maleate.
(FR)Une matrice polymere de diffusion pour administrer un medicament se compose d'environ 2 a 60% d'un plastifiant polaire, par exemple du glycerol, environ 6 a 20% d'alcool polyvinylique, d'environ 2 a 10% de pyrrolidone polyvinylique, et une quantite pharmaceutiquement effective d'un medicament, resultant en une matrice capable de liberer de maniere soutenue un medicament vasodilateur disperse a l'interieur de cette matrice, et le solde etant constitue par de l'eau, les pourcentages etant ponderes. Les medicaments consistent en terbutaline, ephedrine, clonidine, phenylephrine, des esters d'espradiol, la phenylepropanolamine et le maleate de chlorpheniramine.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)