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1. (WO1981003658) DIPHENYLBUTYL-1-ACYLPIPERAZINES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1981/003658    International Application No.:    PCT/SE1981/000169
Publication Date: 24.12.1981 International Filing Date: 05.06.1981
IPC:
C07D 295/185 (2006.01), C07D 295/192 (2006.01)
Applicants:
Inventors:
Priority Data:
8004465 16.06.1980 SE
Title (EN) DIPHENYLBUTYL-1-ACYLPIPERAZINES
(FR) DIPHENYLBUTYL-1-ACYLPIPERAZINES
Abstract: front page image
(EN)Compounds having the general formula (FORMULA) wherein R" is alkyl straight or branch chained having from 2 to 10 carbon atoms, preferably 2-3 carbon atoms, cycloalkyl having from 3 to 8 carbon atoms, preferably 3 carbon atoms, aralkyl having from 7 to 9 carbon atoms or phenyl unsubstituted or substituted by one to three F, Cl, Br, lower alkyl having from 1 to 5 carbon atoms, lower alkoxy having from 1 to 5 carbon atoms, alkylenedioxy having from 1 to 3 carbon atoms, -CF3 or -CN substituents and pharmaceutically acceptable salts thereof and processes for their preparation. Pharmaceutical compositions containing said compounds. Methods of treatment of humans and animals by such compounds and composition. The compounds have anti-aggressive, antipsychotic, antidepressive properties and analgetic properties.
(FR)Composes ayant la formule generale (FORMULE) ou R" est un alkyle a chaine droite ou ramifiee ayant de 2 a 10 atomes de carbone, de preference 2-3 atomes de carbone, un cycloalkyle ayant de 3 a 8 atomes de carbone de preference 3 atomes de carbone, un aralkyle ayant de 7 a 9 atomes de carbone ou un phenyle non substitue ou substitue par l"un des trois elements F, Cl, Br, un alkyle inferieur ayant de 1 a 5 atomes de carbone, un alkoxy inferieur ayant de 1 a 5 atomes de carbone, un alkylenedioxy ayant de 1 a 3 atomes de carbone, des substituants de -CF3 ou -CN et leurs sels pharmaceutiquement acceptables, et leurs procedes de preparation. Compositions pharmaceutiques contenant ces composes. Procedes de traitement d"humains et d"animaux par ces composes et composition. Les composes ont des proprietes anti-agressives, antipsychotiques, antidepressives et analgesiques.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)