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Machine translation
1. (WO1981003174) THIAZOLO(3,2-A)PYRIMIDINE DERIVATIVES,PROCESS FOR PREPARING SAME,AND DRUG CONTAINING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1981/003174    International Application No.:    PCT/JP1980/000090
Publication Date: 12.11.1981 International Filing Date: 28.04.1980
IPC:
C07D 513/04 (2006.01)
Applicants:
Inventors:
Priority Data:
JP80/00090 28.04.1980 WO
Title (EN) THIAZOLO(3,2-A)PYRIMIDINE DERIVATIVES,PROCESS FOR PREPARING SAME,AND DRUG CONTAINING SAME
(FR) DERIVES DE THIAZOLO (3,2-A) PYRIMIDINE, LEUR PROCEDE DE PREPARATION, ET MEDICAMENTS LES CONTENANT
Abstract: front page image
(EN)Thiazolo (3, 2-a) pyrimidine derivatives represented by the following general formula (I): (FORMULA) wherein R represents a phenyl group or a benzyl group containing a substituent of a halogen atom, a lower alkyl group or lower alkoxy group, an alicyclic group, or an arylethyl group, and a process for preparing the compounds represented by the general formula (I) which comprises subjecting the compound, represented by the following general formula (II): (FORMULA) wherein R is the same as defined above, and R" represents a halogen atom or a lower alkyloxy group, to a cyclization reaction under heating. Drugs containing the compounds as effective ingredients are useful for treating autoimmune diseases such as rheumatic arthritis, nephritis, etc.
(FR)Derives de thiazolo (3,2-a) pyrimidine representes par la formule generale suivante (I): (FORMULE) ou R represente un groupe phenyle ou un groupe benzyle contenant un substituant d"un atome d"halogene, un groupe alkyle inferieur ou un groupe alcoxy inferieur, un groupe alicyclique, ou un groupe arylethyle, et un procede de preparation des composes representes par la formule generale (I) qui consiste a soumettre le compose represente par la formule generale suivante (II): (FORMULE) ou R est identique a celui qui a ete defini ci-dessus, et R" represente un atome d"un halogene ou un groupe alkyloxy inferieur, a une reaction de cyclisation sous apport de chaleur. Des medicaments contenant les composes sont utiles pour le traitement de maladies auto-immunes telles le rhumatisme articulaire, la nephrite, etc.
Designated States:
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)