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Machine translation
1. (WO1981002899) MONOCLONAL ANTIBODY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1981/002899    International Application No.:    PCT/GB1981/000067
Publication Date: 15.10.1981 International Filing Date: 13.04.1981
IPC:
C07K 16/24 (2006.01)
Applicants:
Inventors:
Priority Data:
8012096 11.04.1980 GB
Title (EN) MONOCLONAL ANTIBODY
(FR) ANTICORPS MONOCLONAL
Abstract: front page image
(EN)Monoclonal antibody characterised by its specificity to interferon-(Alpha)(leukocyte interferon). Preferably the antibody has specificity to human interferon-(Alpha). The monoclonal antibody is secreted by a hybrid cell formed by the fusion of lymphocyte cells derived from an animal immunized with interferon-(Alpha), with mycloma cells. The antibody has applications in the purification of interferon. It may be covalently attached to a solid support and used as an immuno-adsorbent. Purifications of up to 5000 fold may be obtained in a single pass through an immunoadsorption column of this type. An immunoradiometric assay for interferon-(Alpha) is also described.
(FR)Un anticorps monoclonal est caracterise par sa specificite a l'interferon-(Alpha)(interferon leucocyte). De preference, l'anticorps possede une specificite a l'interferon-(Alpha) humain. L'anticorps monoclonal est secrete par une cellule hybride formee par la fusion des cellules lymphocytes derivees d'un animal immunise avec l'interferon(Alpha), avec les cellules mycloma. L'anticorps presente des applications a la purification de l'interferon. Il peut etre lie par covalence a un support solide et etre utilise comme immuno adsorbant. Des purifications jusqu'a 5000 fois peuvent etre obtenues dans un seul passage par une colonne d'immuno-adsorption de ce type. Un effet immunoradiometrique pour l'interferon-(Alpha) est egalement decrit.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)