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Machine translation
1. (WO1981002012) NEW 2-AMINO METHYL-6-HALOGENOPHENOLS,PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1981/002012    International Application No.:    PCT/CH1981/000004
Publication Date: 23.07.1981 International Filing Date: 13.01.1981
IPC:
C07C 37/045 (2006.01), C07C 37/055 (2006.01), C07C 37/20 (2006.01), C07C 37/62 (2006.01), C07C 43/21 (2006.01), C07C 43/23 (2006.01), C07C 45/46 (2006.01), C07C 49/83 (2006.01)
Applicants:
Inventors:
Priority Data:
267/80 14.01.1980 CH
Title (EN) NEW 2-AMINO METHYL-6-HALOGENOPHENOLS,PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF
(FR) NOUVEAUX 2-AMINO METHYL - 6 - HALOGENOPHENOLS, LEUR PREPARATION ET LEURS COMPOSITIONS PHARMACEUTIQUES
Abstract: front page image
(EN)The new compounds are represented by the formula I: (FORMULA) wherein A or B represents X and the other: (FORMULA) formulas wherein: either X is bromine, n = 1 or 2, R1 and R2 both represent H or methyl or R1 or R2 represent H and the other one methyl, R3 both represent either H or a linear alkyl group C1-4; or X represents iodine, n = 1, R1 and R2 both represent H and R3 both represent an alkyl group C1-4 or R1 and R2 both represent methyl or R1 or R2 represents H and the other methyl, R3 both represent either H or an alkyl group C1-4; or n = 2, R1 or R2 represents H and the other one methyl or R1 and R2 represent methyl, R3 both represent either H or an alkyl group C1-4. The compounds as well as the acid salts pharmaceutically acceptable are appropriate for use as salidiuretic and antihypertensive agents.
(FR)Les nouveaux composes repondent a la formule I: (FORMULE) dans laquelle A ou B represente X et l"autre: (FORMULE) formules dans lesquelles: soit X represente le brome, n = 1 ou 2, R1 et R2 representent tous les deux H ou methyl ou R1 ou R2 represente H et l"autre methyl, R3 representent tous les deux soit H ou un groupe alkyl lineaire C1-4; soit X represente l"iode, n= 1, R1 et R2 representent tous les deux H et R3 representent tous les deux un groupe alkyl C1-4 ou R1 et R2 representent tous les deux methyl ou R1 ou R2 represente H et l"autre methyl, R3 representent tous les deux soit H ou un groupe alkyl C1-4; soit n=2, R1 ou R2 represente H et l"autre methyl ou R1 et R2 representent methyl, R3 representent tous les deux soit H soit un groupe alkyl C1-4. Les composes ainsi que les sels d"acides pharmaceutiquement acceptables sont utilisables comme salidiuretiques et antihypertensifs.
Designated States:
Publication Language: German (DE)
Filing Language: German (DE)