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Machine translation
1. (WO1981001285) SUBSTITUTED CARBOXYLIC CETO-ACIDS,PROCESS FOR THE PREPARATION THEREOF,USE THEREOF AND MEDICINAL COMPOSITIONS CONTAINING THEM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1981/001285    International Application No.:    PCT/EP1980/000123
Publication Date: 14.05.1981 International Filing Date: 31.10.1980
IPC:
C07C 29/36 (2006.01), C07C 59/84 (2006.01), C07C 59/88 (2006.01), C07C 59/90 (2006.01), C07F 3/02 (2006.01), C07F 3/08 (2006.01)
Applicants:
Inventors:
Priority Data:
9785/79 31.10.1979 CH
Title (EN) SUBSTITUTED CARBOXYLIC CETO-ACIDS,PROCESS FOR THE PREPARATION THEREOF,USE THEREOF AND MEDICINAL COMPOSITIONS CONTAINING THEM
(FR) CETO-ACIDES CARBOXYLIQUES SUBSTITUES - PROCEDES DE LEUR PREPARATION - LEUR UTILISATION ET COMPOSITIONS MEDICAMENTEUSES LES CONTENANT
Abstract: front page image
(EN)Substituted carboxylic ceto-acids having the formula I (FORMULA) wherein R1 represents a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl, lower alkyloxy or trifluoromethyl residue. R2 represents a hydrogen or halogen atom and n represents an integer from 3 to 8. These acids, as well as the salts thereof exhibit an hypoglycemic activity when applied to living homeothermic organisms. Preparation processes for these new compounds and intermediate compounds of the synthesis thereof are described. A preparation of medicinal compositions containing such acids or the salt thereof is also referred to.
(FR)Ceto-acides carboxyliques substitues de formule I (FORMULE) dans laquelle R1 signifie un atome d"hydrogene, un atome d"halogene, un groupe hydroxyle, un reste alcoyle inferieur, alcoyle-oxy inferieur ou trifluoromethyle, R2 signifie un atome d"ydrogene ou d"halogene et n signifie un nombre entier de 3 a 8. Ces acides, ainsi que leurs sels presentent un effet hypoglycemiant lorsqu"ils sont appliques a des organismes vivants homeothermes. L"on decrit des procedes de preparation de ces nouveaux composes et de composes intermediaires de leur synthese. La preparation de compositions medicamenteuses contenant de tels acides ou leurs sels est egalement evoquee.
Designated States:
Publication Language: German (DE)
Filing Language: German (DE)