WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1981000962) ANTIBIOTIC COMPOUNDS,PROCESS FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF,METHODS OF TREATMENT THEREWITH AND STAPHYLOCOCCUS BACTERIA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1981/000962    International Application No.:    PCT/GB1980/000164
Publication Date: 16.04.1981 International Filing Date: 13.10.1980
IPC:
C07K 14/31 (2006.01)
Applicants:
Inventors:
Priority Data:
7935534 12.10.1979 GB
Title (EN) ANTIBIOTIC COMPOUNDS,PROCESS FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF,METHODS OF TREATMENT THEREWITH AND STAPHYLOCOCCUS BACTERIA
(FR) COMPOSES ANTIBIOTIQUES, LEUR PROCEDE DE PREPARATION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, TRAITEMENTS LES UTILISANT ET BACTERIES DE STAPHYLOCOQUES
Abstract: front page image
(EN)Antibiotic polypeptide compound, or addition salt thereof, having a molecular weight no greater than 10000 and possessing bactericidal and bacteriolytic activities in respect of Gram-positive bacteria, the said compound comprising within the molecular structure thereof amino acid derivative units of formulae (FORMULA) wherein NH2-R1-COOH, NH2-R2-COOH, NH2-R3-COOH, NH2-R4-COOH, NH2-R5-COOH, NH2-R6-COOH and NH2-R7-COOH respectively represent isoleucine, phenylalanine, alanine, aspartic acid, glutamic acid, lysine and glycine and (FORMULA) represents proline. The invention further provides a process for the preparation of antibiotic polypeptides by the aerobic culturing of a strain of S. epidermidis. The invention also provides compositions comprising antibiotic substances and methods of treatment therewith. The invention further provides a new strain of Staphylococcus epidermidis which produces the antibiotic polypeptides, compositions containing the said strain and a method of cosmetic or prophylactic treatment of the human skin with such compositions.
(FR)Compose polypeptide antibiotique, ou son sel d'addition, ayant un poids moleculaire n'excedant pas 10000 et possedant des activites bactericides et bacteriolytiques par rapport aux bacteries a gram-positif, ledit compose comprenant dans sa structure moleculaire des derives d'amino-acides de formule: (FORMULE) ou NH2-R1-COOH, NH2-R2-COOH, NH2-R3-C00H, NH2-R4-COOH, NH2-R5-COOH, NH2-R6-COOH et NH2-R7-COOH representent respectivement l'isoleucine, la phenylanine, l'alanine, l'acide aspartique, l'acide glutamique, la lysine et la glycine, et (FORMULE) represente la proline. Description d'un procede de preparation de polypeptides antibiotiques par culture aerobie d'une souche bacterienne de S. epidermidis. Compositions comprenant des substances antibiotiques et methodes de traitement avec ces compositions. Une nouvelle souche bacterienne de Staphylococcus epidermidis qui produit les polypeptides antibiotiques, compositions contenant ladite souche et methodes de traitement cosmetiques ou prophylactiques de la peau du corps humain avec de telles compositions.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)