WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1981000564) SUBSTITUTED QUINOLINONE-ALKANECARBOXYLIC ACIDS,THEIR PREPARATION AND USE,AND MEDICAMENTS CONTAINING THEM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1981/000564    International Application No.:    PCT/EP1980/000086
Publication Date: 05.03.1981 International Filing Date: 29.08.1980
IPC:
C07D 215/227 (2006.01), C07D 215/38 (2006.01)
Applicants:
Inventors:
Priority Data:
7887/79 30.08.1979 CH
Title (EN) SUBSTITUTED QUINOLINONE-ALKANECARBOXYLIC ACIDS,THEIR PREPARATION AND USE,AND MEDICAMENTS CONTAINING THEM
(FR) ACIDES QUINOLINONE-ALCANE CARBOXYLIQUES SUBSTITUES, LEUR PREPARATION ET UTILISATION, ET MEDICAMENTS LE CONTENANT
Abstract: front page image
(EN)Quinolinone-alkanecarboxylic acids of the formula I (FORMULA) wherein R1, R2 and R3 are identical or different and denote a hydrogen atom, a halogen atom, a hydroxyl group, an alkoxy group with 1 to 4 carbon atoms, an amino group, a dialkylamino group, the alkyl radicals having 1 to 4 carbon atoms, or a nitro group, R4 and R5 are identical or different and denote a hydrogen atom, a halogen atom, an alkoxy group with 1 to 4 carbon atoms, a hydroxyl group, an amino group or a dialkylamino group, the alkyl radicals having 1 to 4 carbon atoms, or R4 and R5 together denote a methylene-dioxy group bonded to two adjacent ring carbon atoms, and A denotes an alkylene group with 1 to 5 carbon atoms, and esters thereof with alkanols with 1 to 5 carbon atoms, and salts thereof with inorganic and organic bases are new compounds. They display a hyperglycaemic action in warm-blooded animals. Processes for the preparation of the new compounds are given.
(FR)Les acides quinolinone-alcane carboxyliques de formule I (FORMULE) dans laquelle R1, R2 et R3 sont identiques ou differents et representent un atome d"hydrogene, un atome d"halogene, un groupe hydroxyle, un groupe alcoxy avec 1 a 4 atomes de carbone, un groupe amino, un groupe dialkyle amino, les radicaux alkyle ayant de 1 a 4 atomes de carbone, ou un groupe nitro; R4 et R5 sont identiques ou differents et representent un atome d"hydrogene, un atome d"halogene, un groupe alcoxy avec 1 a 4 atomes de carbone, un groupe hydroxyle, un groupe amino ou un groupe dialkyle amino, les radicaux alkyle ayant de 1 a 4 atomes de carbone, ou R4 et R5 representent ensemble un groupe methylenedioxy lie a deux atomes de carbone a cycles accoles, et A represente un groupe alkylene avec 1 a 5 atomes de carbone, et leurs esters avec des alcanols ayant de 1 a 5 atomes de carbone, et leurs sels avec des bases inorganiques et organiques, sont des composes nouveaux. Ils possedent une action hyperglycemique chez les animaux a sang chaud. Procedes de preparation de ces nouveaux composes.
Designated States:
Publication Language: German (DE)
Filing Language: German (DE)