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Machine translation
1. (WO1981000261) CHARGE EFFECTS IN IMMUNOASSAYS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1981/000261    International Application No.:    PCT/US1980/000455
Publication Date: 05.02.1981 International Filing Date: 23.04.1980
IPC:
G01N 33/542 (2006.01)
Applicants:
Inventors:
Priority Data:
61099 26.07.1979 US
Title (EN) CHARGE EFFECTS IN IMMUNOASSAYS
(FR) EFFETS DE CHARGES DANS LES IMMUNOANALYSES
Abstract: front page image
(EN)A method for determining a member of a specific binding pair-ligand and receptor (antiligand). Reagents employed include a first modified member which provides an electrical field due to the presence of a plurality of ionic charges and a second modified member labeled with a component of a signal producing system, which system may have one or more components. The average proximity in the assay medium of the first and second modified members is related to the amount of analyte, where the observed signal from the signal producing system is related to the effect of the electrical field on the signal producing system. Also, compositions are provided, as well as reagents, in predetermined ratios for optimizing the signal response to variations in analyte concentration.
(FR)Methode de determination d"un membre d"une paire de liaisons specifiques-liants et recepteurs (anti-liants). Les reactifs utilises comprennent un premier membre modifie qui donne un champ electrique du a la presence d"une pluralite de charges d"ions et un second membre modifie marque avec un composant d"un systeme de production de signaux, lequel systeme peut avoir un ou plusieurs composants. La proximite moyenne dans le milieu d"analyse des premier et second membres modifies est en rapport avec la quantite d"analyte, le signal observe provenant du systeme de production de signaux etant en rapport avec l"effet du champ electrique sur le systeme de production de signaux. De meme, des compositions ainsi que des reactifs sont prevus dans des rapports predetermines pour optimiser la reponse des signaux aux variations de concentration en analyte.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)