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Machine translation
1. (WO1980002421) PROCESS FOR PRODUCING N-ACYL-D-PHENYLALANINE ESTER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1980/002421    International Application No.:    PCT/US1980/000488
Publication Date: 13.11.1980 International Filing Date: 28.04.1980
IPC:
C12P 13/04 (2006.01), C12P 13/22 (2006.01)
Applicants:
Inventors:
Priority Data:
37162 08.05.1979 US
Title (EN) PROCESS FOR PRODUCING N-ACYL-D-PHENYLALANINE ESTER
(FR) PROCEDE DE PRODUCTION D"UN ESTER DE N-ACYL-B-PHENYLALANINE
Abstract: front page image
(EN)A racemic mixture of N-acetyl-D,L-phenylalanine methyl ester is provided and subjected to the action in an aqueous system of microbially derived serine proteinase. The N-acetyl-L-phenylalanine methyl ester is selectively converted to N-acetyl-L-phenylalanine, which is separated from the unreacted N-acetyl-D-phenylalanine methyl ester, which is then separately recovered. Recycle of either a D or an L component, with racemization to provide a D,L mixture, affords methods of completely converting an original racemic mixture to either optically active isomer form as needed.
(FR)Un melange racemique d"un ester de methyle N-acetyl-B,L-phenylalanine est soumis a l"action dans un systeme aqueux d"une proteinase serine d"origine microbienne. L"ester de methyle N-acethyl-L-phenylalanine est converti de maniere selective en N-acethyl-L-phenylalanine, qui est separe de l"ester de methyle N-acethyl-B-phenylalanine n"ayant pas reagit, et est ensuite recupere separement. Le recyclage d"un composant D ou d"un composant L avec racemisation pour obtenir un melange D, L, permet des methodes de conversion totale d"un melange d"origine racemique dans les deux formes d"isomere optique, selon les besoins.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)