WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1980002295) 4-TRIFLUOROMETHYLCOUMARIN PEPTIDE DERIVATIVES AND THEIR USE IN PROTEINASE ASSAYS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1980/002295    International Application No.:    PCT/US1980/000430
Publication Date: 30.10.1980 International Filing Date: 16.04.1980
IPC:
C07D 311/16 (2006.01), C07K 5/06 (2006.01), C07K 5/08 (2006.01), C12Q 1/37 (2006.01)
Applicants:
Inventors:
Priority Data:
32444 23.04.1979 US
Title (EN) 4-TRIFLUOROMETHYLCOUMARIN PEPTIDE DERIVATIVES AND THEIR USE IN PROTEINASE ASSAYS
(FR) DERIVES DE PEPTIDES DE 4-TRIFLUOROMETHYLCOUMARINE ET LEURS UTILISATIONS DANS LES ANALYSES DE PROTEINASE
Abstract: front page image
(EN)Method for determining the presence of an enzyme in a biological fluid, which includes the steps of contacting the fluid with a synthetic chromogenic substrate, which is an amino acid derivative of 7-amino-4-trifluoromethylcoumarin; incubating the substrate-containing fluid to effect enzymatic hydrolysis; and fluorometrically determining the presence of the free 7-amino-4-trifluoromethylcoumarin chromophore in the hydrolyzate.
(FR)Methode de determination de la presence d"une enzyme dans un fluide biologique qui consiste a mettre en contact le fluide avec un substrat chromogene synthetique, qui est un derive d"un amino acide de 7-amino-4-trifluoromethylcoumarine, a incuber le fluide contenant le substrat pour effectuer l"hydrolyse enzymatique, et a determiner par fluorometrie la presence du chromophore libre de 7-amino-4-trifluoromethylcoumarine dans l"hydrolysat.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)