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Machine translation
1. (WO1980001685) RADIOLABELED AMINE COMPOUNDS AND THEIR USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1980/001685    International Application No.:    PCT/NL1980/000005
Publication Date: 21.08.1980 International Filing Date: 07.02.1980
IPC:
A61K 51/04 (2006.01)
Applicants:
Inventors:
Priority Data:
7900964 07.02.1979 NL
Title (EN) RADIOLABELED AMINE COMPOUNDS AND THEIR USE
(FR) COMPOSES AMINES MARQUES RADIOACTIVEMENT ET LEUR UTILISATION
Abstract: front page image
(EN)Radiolabeled amine compounds, methods for preparing these compounds, diagnostic compositions containing the radiolabeled amine compounds and methods for using these compositions in conducting radiodiagnostic examinations for determining the location and extent of an occurring blood clot in the body of a warm-blooded animal such as a human. The radiolabeled amine compounds of the present invention have the general formula; (FORMULA) wherein X is selected from the group consisting of oxygen; sulfur; lower alkylene, radioactive selenium; and radioactive tellurium, Y is a hydrocarbyl amino group, and when X is oxygen, sulfur or lower alkylene, Y is a radioactive iodine-substituted hydrocarbyl amino group. Also disclosed are pharmaceutically-acceptable, acid addition salts of the above radiolabeled amine compounds.
(FR)Composes amines marques radioactivement, procedes de preparation desdits composes, compositions de diagnostic contenant ces composes amines marques radioactivement et methodes pour l"utilisation de ces compositions dans la conduite d"examens de radio diagnostic pour la determination de l"etendue et de l"emplacement d"un caillot sanguin qui peut se produire dans le corps d"un animal a sang chaud tel qu"un humain. Les composes amines marques radioactivement ont la formule suivante: (FORMULE) dans laquelle X est choisi parmi le groupe consistant en oxygene, soufre, alkylene inferieur, selenium radioactif et tellure radioactif; Y represente un groupe hydrocarbyl amino, et lorsque X represente un atome d"oxygene ou de soufre ou un alkylene inferieur, Y est alors un groupe hydrocarbyl amino substitue par un atome d"iode radioactif. Sont egalement decrits des sels d"addition acide, pharmaceutiquement acceptables, desdits composes amines marques radioactivement.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)