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Machine translation
1. (WO1980000339) PROCESS FOR PREPARING 1-FLUORINATED VITAMIN D COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1980/000339    International Application No.:    PCT/US1979/000529
Publication Date: 06.03.1980 International Filing Date: 24.07.1979
IPC:
A61K 31/593 (2006.01), C07C 401/00 (2006.01)
Applicants:
Inventors:
Priority Data:
928279 26.07.1978 US
Title (EN) PROCESS FOR PREPARING 1-FLUORINATED VITAMIN D COMPOUNDS
(FR) PROCEDE DE PREPARATION DE COMPOSES DE VITAMINE D FLUOREE EN POSITION 1
Abstract: front page image
(EN)New fluorine-substituted vitamin D compounds, methods for preparing such compounds and new fluorinated intermediate compounds used in such methods. The fluorine-substituted vitamin D compounds of this invention are characterized by vitamin D-like activity in their ability to stimulate intestinal calcium transport and bone mobilization and in promoting the calcification of rachitic bone. These compounds would find ready application as a substitute for the vitamin D compounds in the treatment of disease states evincing calcium-phosphorus unbalance and which may be nonresponsive to normal vitamin D therapy.
(FR)Nouveaux composes de vitamine D substitues au fluor, methode de preparation de ces composes et nouveaux composes intermediaires fluores utilises dans de telles methodes. Les composes de vitamine D a substitution de fluor se caracterisent par leur activite identique a celle de la vitamine D pour stimuler le transport intestinal du calcium et sa mobilisation osseuse, et a stimuler la calcification des os rachitiques. Ces composes peuvent s"appliquer comme substituts des composes de vitamine D dans le traitement de maladies temoignant d"un desequilibre calcium-phosphore et pouvant ne pas etre sensibles a une therapie normale a la vitamine D.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)