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1. (US20140134728) METHODS FOR ADJUSTING EXPRESSION OF MITOCHONDRIAL GENOME BY MICRORNA

Application Number: 14122716 Application Date: 01.06.2012
Publication Number: 20140134728 Publication Date: 15.05.2014
Publication Kind : A1
Prior PCT appl.: Application Number:PCTEP2012060336 ; Publication Number: Click to see the data
IPC:
C12N 15/113
[IPC code unknown for C12N 15/113]
CPC:
C12N 15/113
Applicants: Henrion-Caude Alexandra
INSERM (Institut National de la Sante et de la Recherche Medicale)
Bandiera Simonetta
Lyonnet Stanislas
Inventors: Henrion-Caude Alexandra
Bandiera Simonetta
Lyonnet Stanislas
Priority Data:
Title: (EN) METHODS FOR ADJUSTING EXPRESSION OF MITOCHONDRIAL GENOME BY MICRORNA
Abstract:
(EN)

The present invention relates to a method for adjusting the expression of the mitochondrial genome in a human cell comprising a step consisting of modulating the expression of a least one mi RNA selected from the group consisting of hsa-mi R-1973, hsa-mi R-1275, hsa-mi R-494, hsa-mi R-513a-5p, hsa-mi R-1246, hsa-mi R-328, hsa-mi R-1908, hsa-mi R-1972, hsa-mi R-1974, hsa-mi R-1977, hsa-mi R-638, hsa-mi R-1978 and hsa-mi R-1201.