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1. US08644571 - Intensity-modulated proton therapy

Office
United States of America
Application Number 13705903
Application Date 05.12.2012
Publication Number 08644571
Publication Date 04.02.2014
Grant Number 08644571
Grant Date 04.02.2014
Publication Kind B1
IPC
G06K 9/00
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
KRECOGNITION OF DATA; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
9Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
CPC
A61N 5/1039
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
103Treatment planning systems
1039using functional images, e.g. PET or MRI
A61N 5/1031
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
103Treatment planning systems
1031using a specific method of dose optimization
A61N 5/1077
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
1077Beam delivery systems
A61N 2005/1087
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5Radiation therapy
10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
1085characterised by the type of particles applied to the patient
1087Ions; Protons
Applicants Loma Linda University Medical Center
Univeristy of South Australia
Inventors Schulte Reinhard W.
Burachik Regina
Kaya Yalcin
Agents Knobbe, Martens, Olson & Bear LLP
Title
(EN) Intensity-modulated proton therapy
Abstract
(EN)

The therapeutic treatment of a patient using intensity-modulated proton therapy is described. In one example, a method of creating a proton treatment plan is presented that divides volumes of interest into sub-volumes, applies dose constraints to the sub-volumes, finds one or more feasible configurations of a proton therapy system, and selects a proton beam configuration that improves or optimizes one or more aspects of proton therapy. In some implementations, the method of dividing volumes into sub-volumes includes creating fractional sub-volumes based at least in part on proximity to a target volume boundary. In some implementations, the method of finding an improved or optimal proton beam configuration from a set of feasible configurations includes finding a minimum of a cost function that utilizes weighting factors associated with treatment sites.


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