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1. (US20140010830) Non-Coding Immunomodulatory DNA Construct

Office : United States of America
Application Number: 13996791 Application Date: 23.12.2011
Publication Number: 20140010830 Publication Date: 09.01.2014
Publication Kind : A1
Prior PCT appl.: Application Number:PCTEP1174033 ; Publication Number: Click to see the data
IPC:
C12N 15/117
A61K 39/00
A61K 31/711
A61K 45/06
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
117
Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7088
Compounds having three or more nucleosides or nucleotides
711
Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
CPC:
C12N 15/117
A61K 45/06
A61K 39/00
A61K 31/711
Applicants: Schroff Matthias
MOLOGEN AG
Kleuss Christiane
Kapp Kerstin
Inventors: Schroff Matthias
Kleuss Christiane
Kapp Kerstin
Priority Data: 1021867.5 23.12.2010 GB
Title: (EN) Non-Coding Immunomodulatory DNA Construct
Abstract: front page image
(EN)

The present invention relates to a nucleic acid molecule and its use for the modulation of the immune system. It provides a DNA construct for immunomodulation comprising at least one nucleotide in L-conformation.


Also published as:
CA2822377EP2655623JP2014504158SG191328MX343918RU2013132151
KR1020130126680RU0002583291KR1020160113332AU2011347095DK2655623ES2618783
ID2016/01789IL227105CN107299101CN107384930IN6051/DELNP/2013BR112013015816
WO/2012/085291