US20130281701 CRYSTAL FORMS OF ANAMORELIN

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United States of America

Application Number 13919518

Application Date 17.06.2013

Publication Number 20130281701

Publication Date 24.10.2013

Publication Kind A1

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CPC

Applicants Lorimer Keith
Helsinn Therapeutics (U.S.), Inc.
Philipson Marcia
Paul Bernhard
Littler Benjamin

Inventors Lorimer Keith
Pines Seemon H.
Philipson Marcia
Paul Bernhard
Littler Benjamin

Title

(EN) CRYSTAL FORMS OF ANAMORELIN

Abstract

(EN)

Crystalline forms of anamorelin which are useful as pharmaceutical agents are disclosed. Methods of production and isolation of these polymorphs and pharmaceutical compositions which include these polymorphs and pharmaceutical methods of treatment are also disclosed. The crystalline polymorphs of the present invention are useful as they act directly on the pituitary gland cells to release growth hormone.

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
401	Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02	containing two hetero rings
06	linked by a carbon chain containing only aliphatic carbon atoms

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
401	Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02	containing two hetero rings
06	linked by a carbon chain containing only aliphatic carbon atoms

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
401	Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02	containing two hetero rings
06	linked by a carbon chain containing only aliphatic carbon atoms

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
401	Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02	containing two hetero rings
06	linked by a carbon chain containing only aliphatic carbon atoms

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1. US20130281701 - CRYSTAL FORMS OF ANAMORELIN