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1. US20130242313 - SCANNING METHODS AND APPARATUS

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[ EN ]

Claims

1. A method of identifying a region of interest in a sample, comprising:
obtaining one or more optical coherence tomography (OCT) axial scans at one or more locations over the sample surface;
for each axial scan, determining an integrated total of OCT intensity over the depth of the scan, and determining an attenuation depth into the sample at which a predetermined fraction of the integrated total is reached; and
determining from the one or more attenuation depths a region of interest in the sample.
2. The method as claimed in claim 1, further comprising:
generating an image of said sample, in which an indication of said attenuation depth is displayed at each respective location on the sample surface.
3. The method as claimed in claim 2, wherein the attenuation depth is indicated by a colour.
4. The method as claimed in claim 1, further comprising:
for each axial scan, determining an attenuation coefficient by measuring a gradient of the OCT intensity in a region shallower than said attenuation depth.
5. The method as claimed in claim 4, further comprising:
generating an image of said sample, in which an indication of said attenuation coefficient is displayed at each respective location on the sample surface.
6. The method as claimed in claim 5, wherein the attenuation coefficient is indicated by a colour.
7. The method as claimed in any one of the preceding claims, wherein the sample is of tissue from the human or animal body.
8. An optical coherence tomography (OCT) system for scanning a sample, comprising:
a source of broadband light, generating broadband light which is incident on the sample;
an interferometer, for detecting the light scattered from the sample and collating OCT data; and
analysis circuitry, arranged to:
analyse the OCT data to obtain one or more OCT axial scans at one or more locations over the sample surface; and
for each axial scan, determine an integrated total of OCT intensity over the depth of the scan, and determine an attenuation depth into the sample at which a predetermined fraction of the integrated total is reached.
9. The OCT system as claimed in claim 8, further comprising:
a display, for showing an image of said sample in which an indication of said attenuation depth is displayed at each respective location on the sample surface.
10. The OCT system as claimed in claim 9, wherein the attenuation depth is indicated by a colour.
11. The OCT system as claimed in claim 8, wherein the analysis circuitry is further arranged to:
for each axial scan, determine an attenuation coefficient by measuring a gradient of the OCT intensity in a region shallower than said attenuation depth.
12. The OCT system as claimed in claim 11, further comprising:
a display, for showing an image of said sample in which an indication of said attenuation coefficient is displayed at each respective location on the sample surface.
13. The OCT system as claimed in claim 12, wherein the attenuation coefficient is indicated by a colour.
14. A method of identifying a region of interest in a sample substantially as herein described with reference to and/or as illustrated in the accompanying drawings.
15. An optical coherence tomography system substantially as herein described with reference to and/or as illustrated in the accompanying drawings.