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1. (US20120178836) Interconnected porous non-degradable poly(vinyl) alcohol implant and method of manufacture

Office : United States of America
Application Number: 13349365 Application Date: 12.01.2012
Publication Number: 20120178836 Publication Date: 12.07.2012
Grant Number: 08557270 Grant Date: 15.10.2013
Publication Kind : B2
IPC:
C08J 9/26
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
J
WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H142
9
Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
26
by elimination of a solid phase from a macromolecular composition or article, e.g. leaching out
Applicants: Maher Suzanne A.
New York Society for the Ruptured and Crippled Maintaining the Hospital for Special Surgery
Ng Kenneth
Chen Tony
Wanivenhaus Florian
Inventors: Maher Suzanne A.
Ng Kenneth
Chen Tony
Wanivenhaus Florian
Agents: Leason Ellis LLP
Priority Data:
Title: (EN) Interconnected porous non-degradable poly(vinyl) alcohol implant and method of manufacture
Abstract: front page image
(EN)

The present invention relates to a method of manufacture of an interconnected porous non-biodegradable polymer implant suitable for implantation into a mammal for the treatment, repair or replacement of defects or injury in musculoskeletal tissue, wherein the mechanical properties of the implant can be controlled by varying the concentration of the non-biodegradable polymer and/or varying the duration and number of freeze-thaw cycles and the interconnected porous non-biodegradable polymer implant has sufficient percent porosity and pore diameter to facilitate integration of cells and attachment within the mammal via ingrowth of surrounding tissue. The present invention also relates to an implant manufactured by the method.