Processing

Please wait...

Settings

Settings

Goto Application

1. US20100267014 - Method for Prognosis of a Response to a Treatment

Note: Text based on automatic Optical Character Recognition processes. Please use the PDF version for legal matters

[ EN ]

Claims

1. An in vitro method for determining, from a biological sample, the response of a patient suffering from rheumatoid arthritis to a treatment directed against a cytokine involved in the inflammatory process of the disease or for monitoring the response of a patient suffering from rheumatoid arthritis to a treatment directed against a cytokine involved in the inflammatory process of the disease, over time, characterized in that the expression of the gene encoding synoviolin is measured.
2. The method as claimed in claim 1, in which the measurement of the expression of the gene encoding synoviolin comprises the following steps:
a. biological material is extracted from the biological sample,
b. the biological material is brought into contact with at least one specific reagent for the gene encoding synoviolin;
c. the expression of the gene encoding synoviolin is determined.
3. The method as claimed in claim 2, characterized in that the biological material extracted in step a) comprises nucleic acids.
4. The method as claimed in claim 2, characterized in that the at least one specific reagent of step b) comprises at least one hybridization probe.
5. A method for the gene encoding synoviolin, for determining the response of a patient suffering from rheumatoid arthritis to a treatment directed against a cytokine involved in the inflammatory process of the disease or for monitoring the response of a patient suffering from rheumatoid arthritis to a treatment directed against a cytokine involved in the inflammatory process of the disease, over time utilizing at least one specific reagent.
6. A kit for the prognosis of the response of a patient suffering from rheumatoid arthritis to a treatment directed against a cytokine involved in the inflammatory process of the disease, comprising at least one specific reagent for the gene encoding synoviolin.
7. A kit for monitoring the response of a patient suffering from rheumatoid arthritis to a treatment directed against a cytokine involved in the inflammatory process of the disease, comprising at least one specific reagent for the gene encoding synoviolin, as defined above.