US20100151064 Thiazolhydrazides for treatment of neurodegenerative diseases

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United States of America

Application Number 12513480

Application Date 05.11.2007

Publication Number 20100151064

Publication Date 17.06.2010

Grant Number 08410152

Grant Date 02.04.2013

Publication Kind B2

IPC

Applicants Mandelkow Eckhard
Max-Planck-Gesellschaft zur Forderung der Wissenschaften e. V.
Mandelkow Eva-Maria
Technische Universitat Darmstadt
Pickhardt Markus
The Provost Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Biernat Jacek
Lloyd David George
Schmidt Boris
Larbig Gregor

Inventors Mandelkow Eckhard
Mandelkow Eva-Maria
Pickhardt Markus
Biernat Jacek
Lloyd David George
Schmidt Boris
Larbig Gregor

Agents Meyertons, Hood, Kivlin, Kowert & Goetzel, P.C.
Meyertons Eric B.

Priority Data 06022992 05.11.2006 EP

Title

(EN) Thiazolhydrazides for treatment of neurodegenerative diseases

Abstract

(EN)

Described are compounds having a thiazolhydrazide scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said thiazolhydrazide compounds can be used for prophylaxis and/or treatment of neurodegenerative diseases and conditions.

A	HUMAN NECESSITIES
01	AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N	PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43	Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
72	having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms
74	five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
78	1,3-Thiazoles; Hydrogenated 1,3-thiazoles

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41	having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
425	Thiazoles

A	HUMAN NECESSITIES
01	AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N	PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43	Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
72	having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms
74	five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
78	1,3-Thiazoles; Hydrogenated 1,3-thiazoles

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41	having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
425	Thiazoles

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