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1. US20090022734 - Use of EPO receptor activation or stimulation for the improvement of the EDSS score in patients with multiple sclerosis

Office
United States of America
Application Number 12136509
Application Date 10.06.2008
Publication Number 20090022734
Publication Date 22.01.2009
Grant Number 09180165
Grant Date 10.11.2015
Publication Kind B2
IPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 38/19
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
19Cytokines; Lymphokines; Interferons
A61K 38/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
18Growth factors; Growth regulators
Applicants Hannelore Ehrenreich
Inventors Hannelore Ehrenreich
Agents Leydig, Voit & Mayer, Ltd.
Priority Data 07014225 19.07.2007 EP
Title
(EN) Use of EPO receptor activation or stimulation for the improvement of the EDSS score in patients with multiple sclerosis
Abstract
(EN)

The invention provides a method of improving the expanded disability status scale (EDSS) score achieved by mammals affected by multiple sclerosis, in which a substance effecting increased and/or prolonged activation and/or stimulation of the erythropoietin (EPO) receptor is administered to the mammal. In certain embodiments, the substance is administered in intervals which are interrupted by application-free periods of time in which said substance is not administered.

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