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1. (US20090312746) Method and system for preparing soft tissue for grafting, enhancing grafting results, and grafting autologous fat and adipocyte derived stem cells to soft tissue such as the breast and other tissue defects

Office : United States of America
Application Number: 12298011 Application Date: 23.04.2007
Publication Number: 20090312746 Publication Date: 17.12.2009
Grant Number: 09028526 Grant Date: 12.05.2015
Publication Kind : B2
Prior PCT appl.: Application Number:PCTUS2007067202 ; Publication Number: Click to see the data
IPC:
A61M 37/00
A61B 17/00
A61B 19/00
A61B 17/30
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
37
Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
17
Surgical instruments, devices or methods, e.g. tourniquets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
19
Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B1/-A61B18/149
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
17
Surgical instruments, devices or methods, e.g. tourniquets
30
Surgical pincettes
Applicants: Roger Khouri
Inventors: Roger Khouri
Agents: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
Priority Data:
Title: (EN) Method and system for preparing soft tissue for grafting, enhancing grafting results, and grafting autologous fat and adipocyte derived stem cells to soft tissue such as the breast and other tissue defects
Abstract: front page image
(EN)

A method is disclosed for preparing a soft tissue site, and augmenting the soft tissue site, such as the breast(s), scar, depression, or other defect, of a subject through use of devices that exert a distractive force on the breast(s) and grafting of autologous fat tissue such as domes with sealing rims for surrounding each of the soft tissue site and a regulated pump. The method for preparing the soft tissue site, and enhancing fat graft results, entails application of the distracting force to the targeted soft tissue site at least intermittently for some period of time and preferably several weeks prior to the graft procedure. A related aspect of the invention includes following the preparation steps by transfer of fat from other areas of the subject to the subject's soft tissue site, and then reapplication of the distractive force to the soft tissue site that received the autologous fat graft. Alternatively, fat from genetically related sources may be used, and the fat may be further processed prior to injection. Substantial soft tissue augmentation, high rates of graft survival and negligible graft necrosis (data demonstrating 80% survival and only 20% necrosis is presented) or calcification result from the practice of these methods.


Also published as:
EP2029177EP3064223EP3115065WO/2007/124478