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1. US20090257980 - Anti-virus therapy for respiratory diseases

Office United States of America
Application Number 12487563
Application Date 18.06.2009
Publication Number 20090257980
Publication Date 15.10.2009
Grant Number 08273342
Grant Date 25.09.2012
Publication Kind B2
IPC
A61K 38/21
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
19Cytokines; Lymphokines; Interferons
21Interferons
A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Applicants University of Southampton
Inventors Davies Donna Elizabeth
Wark Peter Alexander Blanch
Holgate Stephen
Johnston Sebastian L.
Agents Morrison & Foerster LLP
Priority Data 0405634.7 12.03.2004 GB
518425.4 09.09.2005 GB
Title
(EN) Anti-virus therapy for respiratory diseases
Abstract
(EN)

The present invention provides the use of IFN-β, an agent that increases the expression of IFN-β, or a polynucleotide which is capable of expressing IFN-β or said agent for the manufacture of a medicament for the treatment of rhinovirus-induced exacerbation of a respiratory disease selected from asthma and chronic obstructive pulmonary disease, wherein said treatment is by airway delivery of said medicament, e.g. by use of an aerosol nebulizer. Also provided is IFN-λ for the same purpose.