US20060292191 Use of nanodispersions in pharmaceutical end formulations

Office

United States of America

Application Number 11446844

Application Date 05.06.2006

Publication Number 20060292191

Publication Date 28.12.2006

Grant Number 07871642

Grant Date 18.01.2011

Publication Kind B2

IPC

Applicants Ciba Specialty Chemicals Corporation
Vesifact AG

Inventors Supersaxo Andreas Werner
Weder Hans Georg
Hüglin Dietmar
Röding Joachim Friedrich

Agents Loggins Shiela A.

Priority Data 98810422 11.05.1998 EP

Title

(EN) Use of nanodispersions in pharmaceutical end formulations

Abstract

(EN)

A nanodispersion comprises

(a) a membrane-forming molecule,
(b) a coemulsifier and
(c) a lipophilic component,
in pharmaceutical end formulations, the nanodispersion being obtainable by
(α) mixing the components (a), (b) and (c) until a homogeneous clear liquid is obtained, and
(β) adding the liquid obtained in step (α) to the water phase of the pharmaceutical end formulations, where steps (α) and (β) may be carried out without high energy mixing or homogenization.

The nanodispersions prepared according to this invention are suitable as transport vehicles for pharmaceutical active agents.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
9	Medicinal preparations characterised by special physical form
10	Dispersions; Emulsions
127	Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
9	Medicinal preparations characterised by special physical form
10	Dispersions; Emulsions
107	Emulsions

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
9	Medicinal preparations characterised by special physical form
48	Preparations in capsules, e.g. of gelatin, of chocolate

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
9	Medicinal preparations characterised by special physical form
48	Preparations in capsules, e.g. of gelatin, of chocolate
52	Sustained or differential release type

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
9	Medicinal preparations characterised by special physical form
48	Preparations in capsules, e.g. of gelatin, of chocolate
52	Sustained or differential release type
66	containing emulsions, dispersions or solutions

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