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1. US20060063783 - Sulphonylpiperidine derivatives containing an alkenyl or alkynyl moiety for use as matrix metalloproteinase inhibitors

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Office United States of America
Application Number 10521069
Application Date 09.07.2003
Publication Number 20060063783
Publication Date 23.03.2006
Publication Kind A1
IPC
C07D 211/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
C07D 211/54
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
04with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
06having no double bonds between ring members or between ring members and non-ring members
36with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
54Sulfur atoms
C07D 213/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
213Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
A61K 31/445
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
445Non-condensed piperidines, e.g. piperocaine
A61P 37/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
C07D 211/96
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
92with a hetero atom directly attached to the ring nitrogen atom
96Sulfur atom
Applicants ASTRAZENECA AB
Inventors Burrows Jeremy Nicholas
Tucker Howard
Brown Simon James
Patel Ian
Agents FISH &; RICHARDSON P.C.
Priority Data 0216382 13.07.2002 GB
Title
(EN) Sulphonylpiperidine derivatives containing an alkenyl or alkynyl moiety for use as matrix metalloproteinase inhibitors
Abstract
(EN)

A compound of formula (1): wherein B is optionally substituted C2-4alkenyl or C2-4alkynyl; useful in the inhibition of one or more metalloproteinases and in particular TACE.

Also published as
AU2002368038
AU2003246933
BRPI0312615
CA2492251
CN1628061
CN1668302
CO5001127
EP1518798
EP1531821
ID042.402
IL166011
IN46/DELNP/2005
IS7656
JP2004018069
JP2006502990
KR1020050019853
KR1020050024337
MXPA/a/2005/000517
NO20050764
NZ537640
PH1-2005-500024
PL375361
RU2004139043
US20050183375
WO/2004/000692
WO/2004/006927
ZA2005/00210
ZA200500210
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