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1. US20230055908 - Mesylate salt of para-topolin, compositions containing said salt and use thereof

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Office
United States of America
Application Number 17613221
Application Date 22.08.2020
Publication Number 20230055908
Publication Date 23.02.2023
Grant Number 12378247
Grant Date 05.08.2025
Publication Kind B2
IPC
C07D 473/34
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
473Heterocyclic compounds containing purine ring systems
26with an oxygen, sulfur, or nitrogen atom directly attached in position 2 or 6, but not in both
32Nitrogen atom
34attached in position 6, e.g. adenine
CPC
C07B 2200/13
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
2200Indexing scheme relating to specific properties of organic compounds
13Crystalline forms, e.g. polymorphs
C07D 473/34
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
473Heterocyclic compounds containing purine ring systems
26with an oxygen, sulfur or nitrogen atom directly attached in position 2 or 6, but not in both
32Nitrogen atom
34attached in position 6, e.g. adenine
Applicants USTAV EXPERIMENTALNI BOTANIKY AV CR, V. V. I.
Inventors Lucie Plihalova
Marek Zatloukal
Karel Dolezal
Miroslav Strnad
Jan Walla
Jiri Voller
Agents Notaro, Michalos & Zaccaria P.C.
Priority Data PV 2020-277 17.05.2020 CS
Title
(EN) Mesylate salt of para-topolin, compositions containing said salt and use thereof
front page image
Abstract
(EN)

A para-topolin mesylate salt and its crystalline form is disclosed. Cosmetic and therapeutic applications, and compositions containing this compound, are also disclosed. Mesylate salt of para-topolin has a wide range of biological activities, including antioxidative, anti-inflammatory, anti-senescent and anti-aging while showing low toxicity and excellent solubility.
Related patent documents
WO/2021/233486
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