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1. (US20180355353) TRANSCRIPTION TERMINATOR AND USE THEREOF

Office : United States of America
Application Number: 15779902 Application Date: 29.11.2016
Publication Number: 20180355353 Publication Date: 13.12.2018
Publication Kind : A1
Prior PCT appl.: Application Number:PCTUS2016063955 ; Publication Number: Click to see the data
IPC:
C12N 15/113
C12N 15/63
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
113
Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
CPC:
C12N 15/113
C12N 15/63
Applicants: Gen9, Inc.
Inventors: Ishtiaq E. Saaem
Priority Data:
Title: (EN) TRANSCRIPTION TERMINATOR AND USE THEREOF
Abstract: front page image
(EN)

Artificial transcription terminators and their use are provided herein. In one aspect, a non-naturally occurring nucleic acid sequence can comprise a Y-X-Z stem-loop, wherein: Y is a nucleotide sequence of 10 to 30 nucleotides in length; X is a nucleotide sequence of 3 to 12 nucleotides in length, each nucleotide therein not base pairing with any other nucleotide within X; and Z is a nucleotide sequence of 10 to 50 nucleotides in length and having at least 70% complementarity to Y.


Also published as:
EP3384022WO/2017/095793