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13. (US20180182082) SYSTEMS AND METHODS FOR REFLECTANCE-BASED PROJECTION-RESOLVED OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

Application Number: 15852521 Application Date: 22.12.2017
Publication Number: 20180182082 Publication Date: 28.06.2018
Publication Kind : A1
IPC:
G06T 5/00
A61B 5/00
A61B 5/02
G06T 7/00
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
T
IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
5
Image enhancement or restoration, e.g. from bit-mapped to bit-mapped creating a similar image
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
02
Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
T
IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
7
Image analysis, e.g. from bit-mapped to non bit-mapped
CPC:
A61B 2576/02
A61B 5/0066
A61B 5/02007
A61B 5/7203
A61B 5/7271
G06T 2207/10101
G06T 5/009
G06T 7/0012
Applicants: Oregon Health & Science University
Inventors: Yali Jia
Jie Wang
Priority Data:
Title: (EN) SYSTEMS AND METHODS FOR REFLECTANCE-BASED PROJECTION-RESOLVED OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
Abstract: front page image
(EN)

Embodiments provide systems and methods associated with a reflectance-based projection-resolved (rbPR) optical coherence tomography angiography (OCTA) algorithm which uses optical coherence tomography (OCT) reflectance to enhance the flow signal and suppress the projection artifacts in 3-dimensional OCTA. rbPR improves the vascular connectivity and improved the discrimination of the deeper plexus angiograms in healthy eyes, compared to prior PR-OCTA method. Additionally, rbPR removes flow projection artifacts more completely from the outer retinal slab in the eyes with age-related macular degeneration, and preserves vascular integrity of the intermediate and deep capillary plexuses in the eyes with diabetic retinopathy. Additionally, the rbPR method improves the resolution of the choriocapillaris and demonstrates details comparable to scanning electron microscopy.