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1. US10010249 - Systems, methods, and devices for optical coherence tomography multiple enface angiography averaging

Office United States of America
Application Number 15927966
Application Date 21.03.2018
Publication Number 10010249
Publication Date 03.07.2018
Grant Number 10010249
Grant Date 03.07.2018
Publication Kind B1
IPC
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
K
RECOGNITION OF DATA; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
9
Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
3
Apparatus for testing the eyes; Instruments for examining the eyes
10
Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
3
Apparatus for testing the eyes; Instruments for examining the eyes
10
Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
12
for looking at the eye fundus, e.g. ophthalmoscopes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
3
Apparatus for testing the eyes; Instruments for examining the eyes
[IPC code unknown for G06T 7/30]
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
T
IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
7
Image analysis, e.g. from bit-mapped to non bit-mapped
G06K 9/00
A61B 3/10
A61B 3/12
A61B 3/00
G06T 7/30
G06T 7/00
CPC
A61B 3/0041
A61B 3/102
A61B 3/1241
G06T 2207/10101
G06T 2207/30041
G06T 7/0012
Applicants Doheny Eye Institute
Inventors SriniVas R. Sadda
Akihito Uji
Agents Knobbe, Martens, Olson & Bear LLP
Title
(EN) Systems, methods, and devices for optical coherence tomography multiple enface angiography averaging
Abstract
(EN)

The disclosure herein provides methods, systems, and devices for improving optical coherence tomography machine outputs through multiple enface optical coherence tomography angiography averaging techniques. The embodiments disclosed herein can be utilized in ophthalmology for employing optical coherence tomography (OCT) for in vivo visualization of blood vessels and the flow of blood in an eye of a patient, which is also known generally as optical coherence tomography angiography (OCTA). The embodiments disclosed herein can use linear registration, affine registration and/or elastic registration to align a plurality of optical coherence tomography angiography images or videos at corresponding superficial vascular layers having well-defined features or landmarks, and to apply the same linear registration, affine registration and/or elastic registration settings and/or data to corresponding deeper tissue layers, such as the choriocapillaris, which generally do not have well-defined features or landmarks, in order to align a plurality of corresponding deeper tissue layers for the purpose of averaging the images or video to produce a clearer and more accurate image or video of the tissue structure at deeper tissue layers.