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1. (US20170218007) A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE

Office : United States of America
Application Number: 15500620 Application Date: 31.07.2015
Publication Number: 20170218007 Publication Date: 03.08.2017
Publication Kind : A1
Prior PCT appl.: Application Number:PCTIB2015055828 ; Publication Number: Click to see the data
IPC:
C07H 19/10
C07F 9/58
C07F 9/653
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19
Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02
sharing nitrogen
04
Heterocyclic radicals containing only nitrogen as ring hetero atom
06
Pyrimidine radicals
10
with the saccharide radical being esterified by phosphoric or polyphosphoric acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9
Compounds containing elements of the 5th Group of the Periodic System
02
Phosphorus compounds
547
Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
553
having one nitrogen atom as the only ring hetero atom
576
Six-membered rings
58
Pyridine rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9
Compounds containing elements of the 5th Group of the Periodic System
02
Phosphorus compounds
547
Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
6527
having nitrogen and oxygen atoms as the only ring hetero atoms
653
Five-membered rings
CPC:
C07H 19/10
C07F 9/653
C07F 9/585
Applicants: LUPIN LIMITED
Inventors: Bhairab Nath ROY
Girij Pal SINGH
Dhananjai SHRIVASTAVA
Kishor Gulabrao MEHARE
Vineet MALIK
Sharad Chandrabhan DEOKAR
Abhijeet Avinash DANGE
Priority Data: 2479/MUM/2014 01.08.2014 IN
Title: (EN) A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE
Abstract:
(EN)

The present invention pertains to process for preparing nucleoside phosphoramidate and its intermediate. The present invention provides novel intermediate, its process for preparation and its use for the preparation of Sofosbuvir.


Also published as:
AU2015294840EP3174888WO/2016/016865