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1. (US20170191998) Method for diagnostics, treatment and prevention of Parkinson's disease

Office : United States of America
Application Number: 15314240 Application Date: 28.05.2015
Publication Number: 20170191998 Publication Date: 06.07.2017
Grant Number: 10139408 Grant Date: 27.11.2018
Publication Kind : B2
Prior PCT appl.: Application Number:PCTFI2015050374 ; Publication Number: Click to see the data
IPC:
C12Q 1/04
G01N 33/569
A61K 35/741
G01N 33/68
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
02
involving viable micro-organisms
04
Determining presence or kind of micro-organism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
[IPC code unknown for A61K 35/741]
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
CPC:
A61K 35/741
C12Q 1/04
G01N 2800/2835
G01N 2800/50
G01N 33/56911
G01N 33/6896
Y02A 50/475
Applicants: NeuroInnovation Oy
Inventors: Filip Scheperjans
Petri Auvinen
Velma Aho
Pedro Pereira
Kaisa Koskinen
Lars Paulin
Agents: Banner & Witcoff, Ltd.
Priority Data: 20145492 28.05.2014 FI
Title: (EN) Method for diagnostics, treatment and prevention of Parkinson's disease
Abstract: front page image
(EN)

The present invention relates to the field of medicine and in particular to Parkinson's disease (PD). Specifically the present invention relates to methods and means for early detection of PD. The invention relates also to methods and means for treatment or prophylaxis of PD. In the method of the invention a probability of a subject developing or having Parkinson's disease (PD) is determined by measuring the relative abundances of one or multiple microbial tax a in a sample from a subject; and the probability of the subject developing or having PD is determined based on the measured abundances. The present invention provides a novel approach for the diagnostics of PD.


Also published as:
EP3149205WO/2015/181449