US20160311769 Functionalized 1,3-benzene diols and their method of use for the treatment of hepatic encephalopathy

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United States of America

Application Number 14781081

Application Date 09.01.2015

Publication Number 20160311769

Publication Date 27.10.2016

Grant Number

Grant Date 04.04.2017

Publication Kind B2

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Applicants Kannalife, Inc.
KANNALIFE SCIENCES, INC.

Inventors Douglas E Brenneman
William Alvin Kinney
Mark McDonnell
Dean Petkanas

Agents Caesar Rivise, PC

Title

(EN) Functionalized 1,3-benzene diols and their method of use for the treatment of hepatic encephalopathy

Abstract

(EN)

Pharmaceutical compositions of the invention include novel functionalized 1,3-benzenediols having a disease-modifying action in the treatment of hepatic encephalopathy and related conditions. Pharmaceutical compositions of the invention further include novel neuroprotective agents.

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
205	Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
02	not condensed with other rings
04	having no double bonds between ring members or between ring members and non-ring members

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
B	GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
59	Introduction of isotopes of elements into organic compounds

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
249	Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
02	not condensed with other rings
04	1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
205	Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
02	not condensed with other rings
06	having one double bond between ring members or between a ring member and a non-ring member

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
205	Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
02	not condensed with other rings
04	having no double bonds between ring members or between ring members and non-ring members

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1. US20160311769 - Functionalized 1,3-benzene diols and their method of use for the treatment of hepatic encephalopathy

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
397	having four-membered rings, e.g. azetidine