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1. US20150119456 - Tricyclic sulfone compounds and methods of making and using same

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Office
United States of America
Application Number 14372877
Application Date 17.01.2013
Publication Number 20150119456
Publication Date 30.04.2015
Grant Number 09440943
Grant Date 13.09.2016
Publication Kind B2
IPC
C07D 311/94
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
311Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02ortho- or peri-condensed with carbocyclic rings or ring systems
94condensed with rings other than six-membered or with ring systems containing such rings
CPC
C07D 311/94
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
311Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02ortho- or peri-condensed with carbocyclic rings or ring systems
94condensed with rings other than six-membered
Applicants Zafgen, Inc.
Inventors Thomas D. Pallin
Hazel J. Dyke
Susan M. Cramp
Robert Zahler
Agents Goodwin Procter LLP
Title
(EN) Tricyclic sulfone compounds and methods of making and using same
Abstract
(EN)

The invention provides tricyclic sulfone compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various tricyclic compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.
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