US20140364412 Kinase inhibitors

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United States of America

Application Number 14296794

Application Date 05.06.2014

Publication Number 20140364412

Publication Date 11.12.2014

Grant Number 09181242

Grant Date 10.11.2015

Publication Kind B2

IPC

CPC

Applicants CHIESI FARMACEUTICI S.p.A.

Inventors Lilian Alcaraz
Christopher Hurley
Andrew Peter Cridland
Andrew Stephen Robert Jennings

Agents Oblon, McClelland, Maier & Neustadt, L.L.P.

Priority Data 13170937 06.06.2013 EP

Title

(EN) Kinase inhibitors

Abstract

(EN)

This invention relates to compounds and compositions that are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
211	Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
04	with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
06	having no double bonds between ring members or between ring members and non-ring members
36	with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
40	Oxygen atoms

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
471	Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02	in which the condensed system contains two hetero rings
04	Ortho-condensed systems

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
C	ACYCLIC OR CARBOCYCLIC COMPOUNDS
53	Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
02	Formic acid
06	Salts thereof

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
519	Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/ or C07D455/257

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
211	Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
04	with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
06	having no double bonds between ring members or between ring members and non-ring members
36	with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
40	Oxygen atoms

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1. US20140364412 - Kinase inhibitors