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1. US20140275420 - ATOM TRANSFER RADICAL POLYMERIZATION UNDER BIOLOGICALLY COMPATIBLE CONDITIONS

Office
United States of America
Application Number 14239181
Application Date 22.08.2012
Publication Number 20140275420
Publication Date 18.09.2014
Publication Kind A1
IPC
C08F 289/00
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
289Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds not provided for in groups C08F251/-C08F287/169
CPC
C08F 289/00
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
289Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds not provided for in groups C08F251/00 - C08F287/00
Applicants Matyjaszewski Krzysztof
CARNEGIE MELLON UNIVERSITY
Averick Saadyah E.
Simakova Antonina
Inventors Matyjaszewski Krzysztof
Averick Saadyah E.
Simakova Antonina
Title
(EN) ATOM TRANSFER RADICAL POLYMERIZATION UNDER BIOLOGICALLY COMPATIBLE CONDITIONS
Abstract
(EN)

Methods for conducting controlled grafting-from radical polymerizations from biomolecules under conditions that are biologically compatible are described. The methods provide biomolecule-polymer conjugates with highly controlled structures and narrow polydispersities under aqueous reaction conditions and biological temperatures. Biomolecules, such as proteins and nucleotides can be conjugated to polymers with high levels of control.


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