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1. US20140275186 - Non-steroidal compounds as androgen receptor modulators

Office
United States of America
Application Number 14352052
Application Date 17.10.2012
Publication Number 20140275186
Publication Date 18.09.2014
Grant Number 09278942
Grant Date 08.03.2016
Publication Kind B2
IPC
C07D 261/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
261Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
02not condensed with other rings
04having one double bond between ring members or between a ring member and a non-ring member
C07D 261/20
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
261Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
20condensed with carbocyclic rings or ring systems
C07D 271/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
271Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
02not condensed with other rings
061,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
CPC
C07D 261/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
261Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
02not condensed with other rings
04having one double bond between ring members or between a ring member and a non-ring member
C07D 261/20
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
261Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
20condensed with carbocyclic rings or ring systems
C07D 271/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
271Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
02not condensed with other rings
061,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
Applicants FLX Discoveries Oy
Inventors Juha Pulkkinen
Pekka Poutiainen
Tuomas Oravilahti
Jorma Palvimo
Mikael Perakyla
Reino Laatikainen
Tarja Ihalainen
Agents Ziegler IP Law Group, LLC
Priority Data 20116033 18.10.2011 FI
Title
(EN) Non-steroidal compounds as androgen receptor modulators
Abstract
(EN)

This invention relates to novel 4,5-dihydroisoxazoles and 4,5-dihydro[1,2,4]-oxadiazoles of formula (I), to their use as androgenic or antiandrogenic agents or androgen receptor modulators, and to methods of their preparation.


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