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1. TN2013000210 - LEISHMANIA CANINE CHALLENGE MODEL BY SAND FLY BITES

Office Tunisia
Application Number P2013000210
Application Date 14.05.2013
Publication Number 2013000210
Publication Date 10.11.2014
Publication Kind A1
IPC
A01K 67/027
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67Rearing or breeding animals, not otherwise provided for; New breeds of animals
027New breeds of vertebrates
A61K 39/008
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
002Protozoa antigens
008Leishmania antigens
Applicants MERIAL LIMITED
THE GOV.OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT.OF HEALTH & HUMAN SERVICES
Inventors FISHER LAURENT BERNARD
KAMAHWI SHADEN
VALENZUELA JESUS
SUAU HAMIDE ASLAN
Title
(EN) LEISHMANIA CANINE CHALLENGE MODEL BY SAND FLY BITES
Abstract
(EN)

The present invention provides a method for effectively and reproducibly infecting canines with Leishmania infantum using sand flies to vector the parasite. The inventive method comprises several steps, including ensuring canines are naive to Leishmania, infecting the canines using bites of Leishmania-infected sand fly bites, and evaluating successful transmission of the Leishmania parasites.