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1. SG172336 - DIHYDROPYRIDONE AMIDES AS P2X7 MODULATORS

Office Singapore
Application Number 2011045945
Application Date 14.12.2009
Publication Number 172336
Publication Date 28.07.2011
Publication Kind A
CPC
C07D 401/12
C07D 413/12
Applicants F. HOFFMANN-LA ROCHE AG
Inventors BERGER, JACOB
CAROON, JOAN MARIE
KRAUSS, NANCY ELISABETH
LOPEZ-TAPIA, FRANCISCO, JAVIER
WALKER, KEITH, ADRIAN, MURRAY
ZHAO, SHU-HAI
Priority Data 61/203,482 23.12.2008 US
Title
(EN) DIHYDROPYRIDONE AMIDES AS P2X7 MODULATORS
Abstract
(EN)
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4, R5 and Ra are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.

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