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1. SG10201709894R - PREVENTING OR MITIGATING CHEMOTHERAPY INDUCED ALOPECIA USING VITAMIN D

Office Singapore
Application Number 10201709894R
Application Date 29.05.2014
Publication Number 10201709894R
Publication Date 30.01.2018
Publication Kind A1
CPC
A61K 8/67
A61Q 7/00
A61K 9/0014
A61K 31/593
A61K 47/10
Applicants BERG LLC
Inventors NARAIN, NIVEN, RAJIN
MCCOOK, JOHN, PATRICK
JIMENEZ, Joaquin, J.
Priority Data 61/828,448 29.05.2013 US
Title
(EN) PREVENTING OR MITIGATING CHEMOTHERAPY INDUCED ALOPECIA USING VITAMIN D
Abstract
(EN)
144 ABSTRACT PREVENTING OR MITIGATING CHEMOTHERAPY INDUCED ALOPECIA USING VITAMIN D The invention provides methods and pharmaceutical compositions for preventing or mitigating chemotherapy-induced alopecia (CIA). The pharmaceutical compositions of the invention comprise an effective amount of a vitamin D compound in a topical formulation. The invention has broad applications in chemotherapies that induce alopecia, for example taxane based chemotherapy for cervical cancer, endometrial cancer, ovarian cancer, fallopian tube cancer, primary peritoneal carcinoma, soft tissue sarcoma, or bone sarcoma. The pharmaceutical compositions of the invention can be advantageously administered before and/or concurrent with the chemotherapy. [Figure 1]