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1. (SG11201507367P) CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION

Office : Singapore
Application Number: 11201507367P Application Date: 14.03.2014
Publication Number: 11201507367P Publication Date: 29.10.2015
Publication Kind : A1
Prior PCT appl.: Application Number:PCTUS2014029772 ; Publication Number:2014145098 Click to see the data
IPC:
C12N 5/00
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
Applicants: GENENTECH, INC.
Inventors: VIJAYASANKARAN, Natarajan
MEIER, Steven, J.
VARMA, Sharat
YANG, Yi
Priority Data: 61/799,602 15.03.2013 US
Title: (EN) CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION
Abstract:
(EN) (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 18 September 2014 (18.09.2014) WIPOIPCT (10) International Publication Number WO 2014/145098 A1 (51) International Patent Classification: C12N 5/00 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/US2014/029772 14 March 2014 (14.03.2014) English English (30) Priority Data: 61/799,602 15 March 2013 (15.03.2013) US (71) Applicant (for all designated States except AL, AT, BA, BE, BG, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IN, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT; RO, RS, SE, SI, SK, SM, TR, US): GEN- ENTECH, INC. [US/US]; 1 Dna Way, South San Fran- sisco, CA 94080 (US). (71) Applicant (for AL, AT, BA, BE, BG, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IN, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK SM, TR only): F.HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124, CH-4070 Basel (CH). (72) Inventors: VIJAYASANKARAN, Natarajan; c/o Gen- entech, Inc., 1 Dna Way, South San Francisco, CA 94080 (US). MEIER, Steven, J.; c/o Genentech, Inc., 1 Dna Way, South San Francisco, CA 94080 (US). VARMA, Sharat; c/o Genentech, Inc., 1 Dna Way, South San Fran­ cisco, CA 94080 (US). YANG, Yi; c/o Genentech, Inc., 1 Dna Way, South San Francisco, CA 94080 (US). (74) Agents: ZHOU, Jie et al.; Morrison & Foerster LLP, 425 Market Street, San Francisco, CA 94105-2482 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) 00 0\ © o CJ (54) Title: CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION (57) Abstract: Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided.
Also published as:
CA2903596KR1020150131172EP2970875JP2016514461NZ712315AU2014233393
RU2015144172MYPI 2015002349BR112015021993WO/2014/145098