Processing

Please wait...

Settings

Settings

Goto Application

1. RU0002430109 - IMMUNOMODULATORY AND ANTINEOPLASTIC PEPTIDES

Office
Russian Federation
Application Number 2008137968/04
Application Date 23.02.2007
Publication Number 0002430109
Publication Date 27.09.2011
Grant Number
Grant Date 27.09.2011
Publication Kind C2
IPC
C07K 14/435
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
A61P 37/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
02Immunomodulators
04Immunostimulants
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61K 38/17
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
A61K 38/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10Peptides having 12 to 20 amino acids
A61P 35/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
04specific for metastasis
CPC
C07K 14/43509
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
43504from invertebrates
43509from crustaceans
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
Inventors ГЕРРА ВАЛЕСПИ Марибель (CU)
ТОРРЕНС МАДРАСО Исис дель Кармен (CU)
РЕЕС АКОСТА Освальдо (CU)
ГАРАЙ ПЕРЕС Ильда Элиса (CU)
ГИЛЬЕН НЬЕТО Херардо Энрике (CU)
АСЕВЕДО КАСТРО Борис Эрнесто (CU)
УБЬЕТА ГОМЕС Раймундо (CU)
GERRA VALESPI Maribel' (CU)
TORRENS MADRASO Isis del' Karmen (CU)
REES AKOSTA Osval'do (CU)
GARAJ PERES Il'da Ehlisa (CU)
GIL'EN N'ETO Kherardo Ehnrike (CU)
ASEVEDO KASTRO Boris Ehrnesto (CU)
UB'ETA GOMES Rajmundo (CU)
Priority Data 20060047 24.02.2006 CU
Title
(EN) IMMUNOMODULATORY AND ANTINEOPLASTIC PEPTIDES
(RU) ИММУНОМОДУЛИРУЮЩИЕ И ПРОТИВООПУХОЛЕВЫЕ ПЕПТИДЫ
Abstract
(EN)
FIELD: medicine. SUBSTANCE: invention refers to creation of peptides derived from area 32-51 of LALF proteins, deprived of LPS and heparin binding capability, and intensifying antineoplastic and immunomodulatory effect. EFFECT: peptides and their combinations can be applied in cancer treatment, and also in a combination with the other standard therapies. 6 cl, 13 dwg, 1 tbl, 10 ex

(RU)
Изобретение относится к созданию пептидов, происходящих из области 32-51 белка LALF, лишенных способности к связыванию LPS и гепарина, и усиливающих противоопухолевый и иммуномодулирующий эффект. Указанные пептиды и их комбинации могут применяться в лечении рака, так же как и в сочетании с другими стандартными терапиями. 4 н. и 2 з.п. ф-лы, 15 ил., 1 табл.