Processing

Please wait...

PATENTSCOPE will be unavailable a few hours for maintenance reason on Tuesday 25.01.2022 at 12:00 PM CET
Settings

Settings

Goto Application

1. RU0002742333 - OXYSTEROLES AND METHODS OF USING THEM

Office
Russian Federation
Application Number 2018104245
Application Date 06.07.2016
Publication Number 0002742333
Publication Date 07.08.2019
Grant Number
Grant Date 04.02.2021
Publication Kind C2
IPC
A61K 31/575
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
575substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
C07J 9/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
9Normal steroids containing carbon, hydrogen, halogen, or oxygen, substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
A61P 25/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
20Hypnotics; Sedatives
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
CPC
C07J 7/002
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
7Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
0005not substituted in position 21
001substituted in position 20 by a keto group
0015not substituted in position 17 alfa
002not substituted in position 16
C07J 9/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
9Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
005containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
C07J 13/007
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
13Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
007with double bond in position 17 (20)
C07J 31/006
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
31Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
006not covered by C07J31/003
C07J 41/0061
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
41Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
0033not covered by C07J41/0005
0055the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
0061one of the carbon atoms being part of an amide group
C07J 13/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
13Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
005with double bond in position 16 (17)
Inventors САЛИТУРО Франческо Г. (US)
РОБИШО Альбер Жан (US)
МАРТИНЕС БОТЕЛЬЯ Габриэль (US)
ХАРРИСОН Бойд Л. (US)
SALITURO, Francesco, G. (US)
ROBICHAUD, Albert, Jean (US)
MARTINEZ BOTELLA, Gabriel (US)
HARRISON, Boyd, L. (US)
Priority Data 62/189,068 06.07.2015 US
62/332,931 06.05.2016 US
Title
(EN) OXYSTEROLES AND METHODS OF USING THEM
Abstract
(RU) Изобретение относится к соединению формулы (I-C-i) или его фармацевтически приемлемым солям. В формуле (I-C-i) R1 является C1-6 алкилом и R2 является -CH2CF3, этилом, изопропилом или циклопропилом. Изобретение также относится к фармацевтической композиции и способу положительного аллостерического модулирования NMDA-рецептора. Технический результат: получены новые соединения формулы (I-C-i), которые обладают свойством положительного аллостерического модулятора NMDA и могут применяться при лечении NMDA-опосредованных нарушений. 3 н. и 14 з.п. ф-лы, 1 табл., 39 пр.
Related patent documents
SG11201800054XThis application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
BR122021005567This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
PH12020551586This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.