PT1301201 TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE II

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Portugal

Application Number 01951000

Application Date 10.07.2001

Publication Number 1301201

Publication Date 30.03.2007

Publication Kind E

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Applicants UNIV DUKE

Inventors CHEN YUAN-TSONG

Priority Data 21923700 18.07.2000 US

Title

(EN) TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE II

(PT) TRATAMENTO DA DOENÇA DE ARMAZENAMENTO DE GLICOGÉNIO TIPO II

Abstract

(EN) Methods of treating glycogen storage disease type II, by administering acid ±-glucosidase, are described, as are compositions for use in the treatment of glycogen storage disease type II.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38	Medicinal preparations containing peptides
16	Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43	Enzymes; Proenzymes; Derivatives thereof
46	Hydrolases (3)
47	acting on glycosyl compounds (3.2), e.g. cellulases, lactases

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45	Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38	Medicinal preparations containing peptides
04	Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12	Cyclic peptides

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38	Medicinal preparations containing peptides
16	Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43	Enzymes; Proenzymes; Derivatives thereof
46	Hydrolases (3)

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3	Drugs for disorders of the metabolism
08	for glucose homeostasis
10	for hyperglycaemia, e.g. antidiabetics

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1. PT1301201 - TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE II

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Y	ENZYMES
302	Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
01	Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
0102	Alpha-glucosidase (3.2.1.20)