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1. PH1/2010/500827 - 2`-FLUORO-2`-DEOXYTETRAHYDROURIDINES AS CYTIDINE DEAMINASE INHIBITORS

Office
Philippines
Application Number 1/2010/500827
Application Date 16.10.2008
Publication Number 1/2010/500827
Publication Date 25.07.2014
Publication Kind A
IPC
C07H 19/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
A61K 31/706
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants OTSUKA PHARMACEUTICAL CO., LTD.
Inventors TAKASHI TSUKAMOTO
DANA V. FERRARIS
RENA LAPIDUS
GREGORY S. HAMILTON
BRIDGET DUVALL
Agents SYCIP SALAZAR HERNANDEZ AND GATMAITAN
Title
(EN) 2`-FLUORO-2`-DEOXYTETRAHYDROURIDINES AS CYTIDINE DEAMINASE INHIBITORS
Abstract
(EN) The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of making and using such compounds.
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