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1. PH1/2013/500857 - METHODS AND COMPOSITIONS FOR TREATING HIV-ASSOCIATED DIARRHEA

Office Philippines
Application Number 1/2013/500857
Application Date 31.10.2011
Publication Number 1/2013/500857
Publication Date 01.07.2013
Publication Kind A1
IPC
A61P 1/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
12Antidiarrhoeals
Applicants NAPO PHARMACEUTICALS, INC.
SALIX PHARMACEUTICALS, LTD.
Inventors CHATURVEDI, Pravin
FORBES, William
BORTEY, Enoch
KING, Steven
Agents CASTILLO LAMAN TAN PANTALEON & SAN JOSE
Priority Data 61/408,622 31.10.2010 US
61/409,335 02.11.2010 US
61/416,249 22.11.2010 US
61/434,379 19.01.2011 US
Title
(EN) METHODS AND COMPOSITIONS FOR TREATING HIV-ASSOCIATED DIARRHEA
Abstract
(EN)
Presented herein are methods for treating diarrhea by administering to a patient in need thereof, an inhibitor of chloride-ion transport in an amount sufficient to treat diarrhea. Treatment of diarrhea includes the treatment of the diarrhea as well as the pain, abdominal discomfort and other symptoms associated with diarrhea. In one embodiment, the inhibitor of chloride-ion transport is crofelemer.