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1. PE2009-0442 - METODO 925

Office
Peru
Application Number 2008001126
Application Date 03.07.2008
Publication Number 2009-0442
Publication Date 17.05.2009
Publication Kind A1
IPC
G01N 33/50
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G01N 33/53
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
CPC
A61P 3/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
G01N 33/948
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
94involving narcotics ; or drugs or pharmaceuticals, neurotransmitters or associated receptors
948Sedatives, e.g. cannabinoids, barbiturates
G01N 2800/02
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
02Nutritional disorders
G01N 2800/52
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
52Predicting or monitoring the response to treatment; Prognosis
Applicants ASTRAZENECA AB
Inventors BJORN CARLSSON
CECILIA KARLSSON
SVEN SJOGREN
Agents FRANCISCO ESPINOSA BELLIDO
Priority Data 60/947,733 03.07.2007 US
Title
(ES) METODO 925
Abstract
(ES)
SE REFIERE A UN METODO DE TRATAMIENTO PARA INDUCIR LA PERDIDA DE PESO, MANTENIMIENTO DE PESO O AUMENTO DEL MISMO EN UN PACIENTE QUE LO NECESITE QUE COMPRENDE i) DETERMINAR EL NIVEL DE UNO O MAS LIGANDOS CANABINOIDES ENDOGENOS EN CIRCULACION TAL COMO ARAQUIDONOIL ETANOLAMIDA (AEA) Y 2-ARAQUIDONOILGLICEROL (2-AG) EN DICHO PACIENTE MEDIANTE INMUNOENSAYO DE FLUORESCENCIA, INMUNOENSAYO DE LUMINISCENCIA, ELISA, ENTRE OTROS; ii) SELECCIONAR UNA TERAPIA APROPIADA EN BASE AL NIVEL DE LIGANDOS CANABINOIDES ENDOGENOS DETECTADOS QUE EN EL CASO DE SER ALTA SE TRATA CON UN ANTAGONISTA DEL RECEPTOR CANNABINOIDE 1 (CB1R) TAL COMO RIMONABANT, TARANABANT, SURINABANT, ENTRE OTROS