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1. WO2016134373 - LEPTOSPIRA IMMUNOPROTECTIVE PROTEINS AND METHODS OF IDENTIFICATION AND USE THEREOF

Publication Number WO/2016/134373
Publication Date 25.08.2016
International Application No. PCT/US2016/018958
International Filing Date 22.02.2016
IPC
A61K 39/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
C07K 14/20 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
20from Spirochaetales (O), e.g. Treponema, Leptospira
CPC
A61K 2039/54
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
54characterised by the route of administration
A61K 2039/545
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
545characterised by the dose, timing or administration schedule
A61K 39/0208
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
0208Specific bacteria not otherwise provided for
A61K 39/0225
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
0225Spirochetes, e.g. Treponema, Leptospira, Borrelia
A61K 9/0019
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
A61P 31/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
Applicants
  • MERIAL, INC. [US]/[US]
  • CALIXAR [FR]/[FR]
  • GENOSTAR [FR]/[FR]
  • VETAGRO-SUP [FR]/[FR]
  • INSTITUT PASTEUR [FR]/[FR]
Inventors
  • BOMCHIL, Natalia, Ines
  • CLAUDE, Jean-baptiste
  • CUPILLARD, Lionel, Pierre Christian
  • FONTANA, Celia
  • JAWHARI, Anass
  • MANDON, Elodie
  • KODJO, Angeli
  • PICARDEAU, Mathieu
  • ESHGHI, Azad
Agents
  • JARECKI-BLACK, Judy
Priority Data
62/118,79020.02.2015US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) LEPTOSPIRA IMMUNOPROTECTIVE PROTEINS AND METHODS OF IDENTIFICATION AND USE THEREOF
(FR) PROTÉINES IMMUNOPROTECTRICES DE LEPTOSPIRA ET MÉTHODES D'IDENTIFICATION ET D'UTILISATION DE CELLES-CI
Abstract
(EN)
The present invention provides compositions and methods for eliciting heterologous protective immunity in animals against Leptospira spp. The Leptospira spp. immunoprotective peptides disclosed herein elicit protective immunity against subsequent challenge or exposure to at least two Leptospira spp. serovars.
(FR)
La présente invention concerne des compositions et des méthodes pour éliciter une immunité protectrice hétérologue chez des animaux contre Leptospira spp. Les peptides immunoprotecteurs de Leptospira spp. élicitent une immunité protectrice contre une attaque ou une exposition ultérieures à au moins deux sérovars de Leptospira spp.
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